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Please login to access the full content or check if you have access via Method 6: Bis(isopropoxy)titanium(IV)–Propargyl or –Allenyl Complexes by ­Transmetalation of Titanium(IV) Complexes with Propargyl- or ­Allenyllithium Compounds

DOI: 10.1055/sos-SD-002-00576

Mikami, K.; Matsumoto, Y.; Shiono, T.Science of Synthesis, (20032526.

Bis(isopropoxy)titanium(IV)propargyl complexes 146 and allenyl complexes 147 are prepared by reaction of 1-substituted or 1,3-disubstituted prop-1-ynes with tert-butyllithium and followed by reaction with [Ti(OiPr)4] (Scheme 73).[‌281‌] The reactions of 146 or 147 with aldehydes give α-allenyl alcohols or threo-β-acetylenic alcohols, respectively, in high regioselectivities.

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