Science of Synthesis

Tomé, A. C., Science of Synthesis, (2004) 13, 415.

General Introduction

Previously published information regarding this product class can be found in Houben–Weyl, Vol. E 8d, pp 305–405 (1,2,3-triazoles)[‌1‌] and pp 406–478 (benzotriazoles).[‌2‌] Other important reviews on the chemistry of 1,2,3-triazoles and their benzo derivatives are also available.[‌3‌–‌9‌]

8,8,8-Meeeeeeee eee eeeeeeeeeeeeee eee eeeeeeeee eeeee ee eeeeeeeeeeee eeeeeeeee. Meee eeee eeeeeeee eeeeeeeeeeee ee eeeeeeee, eeeeee ee eeeeeeeee, eeeeeeeeeee eeeeeeeee, eeeeeeeeeeeeeeee ee eeeeeeee, eeeeeee eeeeeeeeeee eeeeee, eeeeeeeee eeeeeeeeee eee ee eeeeeeeeeeee eeeeeeeeeeeeee.[‌8‌,‌8‌] Meee, eee ee eeeee eeeeeeeee eeeeeeeeee eeeeeeeeee, eeee eeee eeeeeeeeee eeeeeeeeeee ee eeeeeeee eee ee eeeeeeeeeeeee.[‌8‌,‌8‌] Meeeee eeee, eeeee eeeeeeeee eee eeeeeeeeeee eeeeeee ee eeee eeeeeeee eeeeee eee ee eeeee eeeeeeeeeee eeeeeeee eee eeeeeeeee eeeeeeeeee.

Mee 8,8,8-eeeeeeeee eee ee eeeeeee ee eeeee eeee eeeeee: eeeeeeeeee 8,8,8-eeeeeeeee, eeeeeeeeeeeeee, eee 8,8,8-eeeeeeeeee eeeee. Me eeeeeeeee ee ‌Meeeee 8‌, eee eeeeeeeeee 8,8,8-eeeeeeeee eeeee eeeeeeeeee eee ee eeeeeeeeee, eeeeeeeee ee eee eeeeeeee ee eee eeeeeeeeeeee ee eee eeee. Meeee 8M- eee 8M-8,8,8-eeeeeeeee eee eeeeeeee eeeeeeeee eeeee 8M-eeeeeee eee eee. Meee eeee ee eeeeeeeee ee eee eeeeeeeee ee eeeeeeee ee 8M- eee 8M-8,8,8-eeeeeeeee eee eee eeeeee ee 8M-8,8,8-eeeeeeeee.[‌8‌] Me eee eeeeeeeeee, eee 8,8,8-eeeeeeee eeeeee ee eeeeeeeee eeeee ee “e-eeeeeeee” ee eeeee ee eeeeeeeeeee ee eeee “e-eeeeeeee”, eee 8,8,8-eeeeeeee eeeeee.

‌Meeeee 8‌ Meeeeee ee 8,8,8-Meeeeeeee

M-Meeeeeeeeeeee 8,8,8-eeeeeeeee eee ee eeeeeeee eeeeee ee 8M- ee ee 8M-eeeeeeeeeee eeeee eeeee eee eeeeeeeeee eeeee eee ee eeeeeeeeeee, eeee ee eeeeeeee eee ee eee eee eeeee (‌Meeeee 8‌). Me eeee eeeeeee, eee eeeeeeeeeeeeee, eeee eeee ee eeeeeeee eeee ee eeeeeeeeeee ee 8M-eeeeeeeee, eeeeeeeeeeeee ee eee eeeeeeeeeee eeeeeeee.

‌Meeeee 8‌ Meeeeeeeeee ee 8,8,8-Meeeeeeee

Mee eee eeeeeeeeee eeeee ee 8,8,8-eeeeeeee eee eeeeeeeeeeeee eee ee eeeeeeeeeee, eeee ee eeeeeeee eee ee eee eee eeeee (‌Meeeee 8‌). Meeeeee eeeee ee ee eeeeeeeeeeeee eeeeeeeeee ee eeeeeeeee eeeeeee 8,8,8-eeeeeeee eee eeeeeeeeeeeee eeeeeeeee. Me eee eee eeeee, eee 8M-eeeeeeee ee 8,8,8-eeeeeeee eeeeeeeeee eeee eeee 88.8% ee eee eeeeeeeeeee eeeeeee, eeeeeee ee eeeeeeeeeeeee eee 8M-eeeeeeee ee eee eeeeeeeeeee eee (eeee eeee 88.88% ee eeeeeeeeeee).[‌88‌] Me eeeeeeee, eee eeee eeeeee eeeeee eeeeee ee 8M-eeeeeeeee eeeee eeeee eeeeeeeeee eee, ee e eeeeeeeeeee, eeeeeeee ee 8M- eee 8M-8,8,8-eeeeeeee eee eeeeeeee ee eeeeeeee eeeeeee eee eeeeee eeeeeeeee ee 8M-eeeeeeeeeeeee ee eeeeeeeeee.[‌88‌] Me eee eeeee eeeee, 8,8,8-eeeeeeee eeeeee ee e 8:8 eeeeeee ee 8M- eee 8M-eeeeeeeee, eeeee 8-eeeeee-8,8,8-eeeeeeee eee 8-eeeee-8,8,8-eeeeeeee eee, eeeeeeeeeeee, ee eee 8M- eee 8M- eeeeeeeeee eeeee.[‌88‌] Mee eeeeeeeeeeee eeeeee eeeeee ee eeeeeee eee eee eeeeeeeeee eeeeeee ee 8M- eee 8M-8,8,8-eeeeeeee ee 8.88 M ee 88°M eee 8.88 M ee 88°M. Mee eeeeeeeeeeee eeeeee eeeeeee eee ee eeeeeee: 8M-8,8,8-eeeeeeee 8.88 M, 8M-8,8,8-eeeeeeee 8.88 M, 8M-eeeeeeeeeeeee 8.88 M, eee 8-eeeeee-8M-eeeeeeeeeeeee 8.88 M.[‌8‌]

8M-8,8,8-Meeeeeee ee eeee e eeee eeee (eMe 8.88) eee e eeee eeee (eMe 8.8) ee eeeeeeeeee eeeeeeee ee eeeeee. 8M-8,8,8-Meeeeeee-8,8-eeeeeeeeeeeeee (eMe 8.88), 8,8-eeeeeee-8M-8,8,8-eeeeeeee (eMe 8.88), eee 8-eeeee-8M-8,8,8-eeeeeeee (eMe 8.88) eee eeee eeee eeeeee eeeeeeeee. 8-Meeeee-8M-8,8,8-eeeeeeee (eMe 8.88) eeeee e eeeeeeee eeeeeeeeee ee 8M-8,8,8-eeeeeeee, eee 8-eeeeee-8M-8,8,8-eeeeeeee ee e eeee eeeeee eeee.[‌88‌–‌88‌] Mee eeeeeeee ee M-eeeeeeeeeeeee eee M-eeeeee-8,8,8-eeeeeeeee ee eee eee eeeee, ee eeeeeeee, eee ee eee eeeee eeeee eee eeee eeeeeeeeee.[‌88‌] Mee eeeee eeeeeee eeee ee eeeeeeeeeeeee (eMe 8.8) ee eeee-eeeeeeeee eee eeee-eeeeeeeeeeeee. Meeeeeeeeeee ee eeeeeeee eeeee ee eeeeeeee ee eee eeeeeee eeee eeeeeee ee eeeeeeeee eeeeeee: 8-eeeeeeeeeeeeeeeeeee, eMe 8.8; 8,8,8,8-eeeeeeeeeeeeeeeeeeeeeeee, eMe 8.8.[‌88‌,‌88‌]

Mee eeeeeeeeeee ee eeee-eeeeeeeee eee ee eeeeee eeeeeee ee eeeeeeeeeee eeeeeeeeeeee eee 8,8,8-eeeeeeeee eee eeeeeeeeeeeeee eee eee eeeeeeeeeee ee e eeeeee ee eeeeeeeeeeee eeeeeeeeee eeee ee eee eeeeeeeeeeeeeeee ee eeeee eeeeeee eeee eeee eeeeeeee.[‌8‌]

8,8,8-Meeeeeeee eeee e eeeeee eeeeeeee-eeeeeeeeeee eeeee ee M8 (e.e., eeeee, eeeee, ee eeeeeeeeeeee eeeeee) eeeeeee eeeee eee eeeeeeeeee eeee eeeeeee ee α-eeeeeeeeee eeeeeeeee (‌Meeeee 8‌). Meee eeee–eeeee eeeeeeeeeee, eeee eeeeeeee ee eeee eeeeeeeeeeeee eeeeeeeeeee, ee eeeeeeee eeeeeeeeeee eeeeeeeee.[‌88‌–‌88‌]

‌Meeeee 8‌ Meee–Meeee Meeeeeeeeee ee 8,8,8-Meeeeeeee eee Meeeeeeeeeeeee

Meee eeee ee eeeeeeeeeee ee eeee eeeeeeee, eee eeeeeee, ee eee eeeeeeeeeeeeeee ee 8-eeee-8,8,8-eeeeeee-8-eeeeee eee 8-eeeeeee-8,8,8-eeeeeeeee (M8 = eeee) (‌Meeeee 8‌). Meee eeeeeeeeeeeee ee eeeee ee eee Meeeeee eeeeeeeeeeeee. Me ee eeee eeeeeeee ee eee eeeeeeeeeeeeeee ee eeeeeeeee eeee eeeee eeeeeeeeeeee ee eeeeeeee 8 (ee 8) eee ee eee eeeeeeeeee ee 8,8,8-eeeeeeeee eeee eeeee eeee eeeeeee. Mee eeeeeeeeeee ee eeeeeeeeeee eeeeeeeee, eee eee eeeeeeee ee eeeeeeeeee ee eee eeeeeeee ee eee eeeeeee. Me eeeeeeee, eee eeeeeee, eee eeeeeeeeeee eeeeeeee ee eeeeeee ee eee eeee eeeeee MM eeeeeeeee. Me ee eeee eeeeeeee eeee eeeeeeee-eeeeeeeeeee eeeeee eee eeeee, eeeee eeeeee eeee ee eeeee eee eeeeeeeee eeeeeeee eeeee eeeee eeeeee eeee ee eeeee eee eeeeee eeeeeeee. Meee eeeeeee eee eeee eeeeeeee.[‌88‌]

‌Meeeee 8‌ Meeeeee Meeeeeeeeeeee ee 8,8,8-Meeeeeeee

Me eeeee ee eeeeeeeee, eeeeeeeeee 8,8,8-eeeeeeeee eee eeeeeeeeeeeeee eee eeeeeeeeee eeeeee eeeeeeeee. Mee eeeeeeee eeee ee eee eeeeeeee eeeeeee ee eeeeeeeeee ee eeeeeeeee eee eeeeeeeee eeeeeeee eeee eeeeee eeeee eeeeeee eeeeeeeeee. Mee eeeeeeee ee eeeeeeeeeeee eeee eeee e eeeeeeeeeeeee eeeeee ee eee eeee eeeeee eee eeeeeeeeee eee eeeeeeee. Meee eeeeeeeee ee eeeeeeeee ee eeeeeeeeee, 8,8,8-eeeeeeeee eee eeeeeeeeeeeeee eeeeeee eeeeeeee eee eeeeeee eeee eeeeeeee eeeeeee eeeee eeeee eeeeeee ee eeee e eeeee ee eeeeee eeeeeeeee: eeeeeeee, eeeeeeeeeee, eeeeeeee, eeeeeeeee, eeeeeee, eee. Mee eeeeeee ee eeeeeeeeeeeee eeeeeeeee ee eeeeeeee eeee 8-eeeeeeeeeeeeeeeeee eeeee ee eee eeeeeeeee ee eeeeeeeeee (‌Meeeee 8‌).

‌Meeeee 8‌ Meeeeeeeee ee 8-Meeeee-8-(8-eeeeeeeeeeee)-8M-eeeeeeeeeeeee

Meee eeeeeeeeee 8,8,8-eeeeeeeee eee eeeeeeeeeeeeee eee eeeeeee eeeeeeeee ee eeeeeeee ee eeeee eeeeeee, eeeeeeee eeeeeee, eeeeeeeeeeee, eeeeee eeeeeeeeee, eee eeeee eeeeeeeeee eeeeee; eeeeeeeee eeeeeeee ee eee eeeeeeee M-eeeee eeeeeee eee eeeeeeee. Meee eeee eeeeeeee eeeeeeee, ee eeeee eeeeeee eeeeeeee eeeeeeeeee, eeeeeeeeee eeeee eee eeeeeeee. M-Meeeeeeee ee eeee eeeeeeee ee eeeeeeeee eeee eeeeeee eee eeee. 8,8,8-Meeeeeeee eee eeeeeeeeeeeeee eeee eeeee eeee eeee eeeeeee eee eeeeeeeeee ee eeeeeee eee eeeeeeeeeeeee M-eeee eeeeeeeeeee. Meeee eeeeeeeee eeee eeeee eeee eeeeeeee eeeeeeeee, eeeeeeeeeee, eeeeeeeeeeeeeeeeeeeee, eee. ee eeee eee eeeeeeeeeeeee M-eeeeeeeeeee eeeeeeeeeee. Meeeeeeeeeeee eeeeeeeeeeee ee MM eeeeeeeee ee eeee eeeeeeee: eeeeeeeeeeee eee eeeeeeeee eee eeeeeeee ee eeee eeeeeeeeeeeeeee. Meeeeeeeee ee eeeeeeeee eeeeeeee ee eeeeeeee ee eeeeeeeeeeeee eeeeeeee ee eeeeeee eeeeeeeee eeeeeeee ee eeeeeeeeeeeeeeeee ee eeeee eeeeeeeee ee MM eeeeeeeee. Meeeeeeee eee eeee ee eeeeeeeee eeeeee eeeeeeeeeeeee ee eeeeeeeeeeee ee ee M-eeeee eeeee.

Mee eeeee eeeee ee eeeeeeeee, eee eeee eeeeee eeee eeeeeee eee 8,8,8-eeeeeeee eeeeeeeeeee, eee eeeeeeeee ee eeee eeeeeee. Meee, eee eeeeeeeee eeeeeee eeeeeeeee eee eee eeeeeeeeeeee ee eee 8,8,8-eeeeeeee eeee eee eeeeeeee.

References

Meeeeee Meeeeeeeeee

• 8.Meeeee-Meee, (8888) M 8e, 888.