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Please login to access the full content or check if you have access via Variation 3: From Acyl Enamines and Ethene-1,1-diamines

DOI: 10.1055/sos-SD-015-00002

Spitzner, D.Science of Synthesis, (20051571.

2-Nitroethene-1,1-diamine, a nitroketene aminal, behaves as a Michael donor in Michael reactions with acyl enamines, e.g. 245 and 247 (Scheme 80). The secondary amino group of the enamine is lost during the aromatization step and 3-nitropyridines as well as functionalized 3-nitropyridines, e.g. 246 and 248, are formed.[‌302‌‌304‌]

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