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15.1.1.4.1.1.7.2 Method 2: Direct Amination or Alkylamination with Alkali Amides (Tschitschibabin Reaction)

DOI: 10.1055/sos-SD-015-00002

Spitzner, D.Science of Synthesis, (200515154.

The classical Tschitschibabin amination is the 2-amination of pyridines, e.g. the amination of 2,3-dimethylpyridine (650) (Scheme 215).[‌793‌,‌794‌] Generally, the amination of pyridines substituted with electron-withdrawing groups may give products which stem from a ring-opening reaction.[‌795‌]

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