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DOI:
10.1055/sos-SD-020-01227
Vanderwal, C. D.; Jacobsen, E. N., Science of Synthesis, (2007) 20, 1320.
Certainly one of the most reliable methods for the introduction of the alk-2-enoic acid ester function is the homologation of aldehydes or ketones by Wittig and related condensation reactions. While the Wittig and Horner–Wadsworth–Emmons reactions are most often used for this purpose, the Horner–Wittig and Peterson reactions have also successfully fulfilled this role.
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