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DOI: 10.1055/sos-SD-025-00247

Göttlich, R.Science of Synthesis, (200725388.

The Grignard reagent 35 can serve as a formal homoenolate equivalent,[‌126‌] and undergoes efficient addition to various aldehydes and ketones to give the corresponding γ-hydroxyaldehyde cyclic acetals 36.[‌127‌] The protecting acetal group can be readily removed by acid hydrolysis (Scheme 31).

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