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DOI:
10.1055/sos-SD-026-00397
Salaün, J., Science of Synthesis, (2005) 26, 564.
Stepwise bromination of pentaerythritol (34) gives pentaerythrityl tetrabromide (35) in 72% yield (Scheme 14).[34] In the presence of activated zinc (HCl), pentaerythrityl tetrabromide (35) undergoes cyclization to provide methylenecyclobutane (36) in 70% yield. Finally, ozonolysis of methylenecyclobutane (36) gives cyclobutanone (3) in 75% yield (Scheme 14).[34]
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References
| [34] | Meeee, M. M.; Meeeeéeeee, M.; Meeeee, M. M., Meee. Mee. Meee. Me., (8888), 8888. |
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- 8.Meeeee-Meee, (8888) 8/8e, 888.
- 8.Meeeee-Meee, (8888) M 88e, 888.
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