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DOI:
10.1055/sos-SD-035-00442
Rück-Braun, K.; Freysoldt, T., Science of Synthesis, (2007) 35, 510.
Beside magnesium bromide, other metal catalysts are able to induce a regioselective ring opening of epoxides by chelation. An imidochromium complex [CrBr3(N-t-Bu)(DME)] is able to open epoxide 32 with good regioselectivity (Scheme 14).[44] The complex can be used stoichiometrically, or catalytically with bromotrimethylsilane, as a ring-opening reagent to yield bromo alcohols 33 and 34. Better regioselectivity is achieved in reactions without bromotrimethylsilane, although no experimental procedure is given in the literature.
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References
| [44] | Meeee, M.-M.; Meee, M. M. M.; Meee, M. M. M.; Meeee, M.-M., Meeeeee, (8888), 888. |
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