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Please login to access the full content or check if you have access via Variation 11: Biocatalytic Oxidation

DOI: 10.1055/sos-SD-036-00003

Porter, M. J.Science of Synthesis, (20083633.

The use of biocatalysis in the oxidation of unactivated CH bonds to alcohols is widespread, and has been the subject of several reviews.[‌91‌‌98‌] Most biocatalytic hydroxylations are carried out with whole-cell systems, primarily due to the complex cofactor requirements of oxidative enzymes and the difficulties encountered in their purification. While a number of bacterial systems have been employed, the most widely used organisms are filamentous fungi,[‌99‌] in particular Beauveria bassiana (previously known as Sporotrichum sulfurescens and latterly B. sulfurescens).[‌100‌]

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