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Please login to access the full content or check if you have access via Variation 4: Sonogashira Reactions in Water or Aqueous Mixtures of Solvents

DOI: 10.1055/sos-SD-043-00304

Griesbeck, A. G.; Soldevilla, A.Science of Synthesis, (200843364.

Sonogashira protocols in aqueous solution are required for some specific syntheses, for example in the bioconjugation of peptides. For this purpose, guanidino phosphines have been developed as water-soluble ligands for palladium(0).[‌75‌]

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