Science of Synthesis

de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 527.

An alternative, indirect possibility to add methylene to a double bond in a tetrasubstituted alkene is by a two-step sequence consisting of an initial dichloro- or dibromocarbene cycloaddition to give a dihalocyclopropane ‌163‌, with subsequent reductive removal of the halogens (‌Scheme 52‌). Although the tremendous increase in the applications of this method (to ca. 300–350 examples) has almost ceased owing to significant improvements in the original Simmons–Smith cyclopropanation, for certain cases it still remains the only viable protocol. Ever since the first preparation of dichlorocyclopropanes ‌163‌ (X = Cl) by Doering and Hoffmann in 1954 (this report is generally conceived to be the very first example of a carbene addition onto a double bond),[‌251‌] gem-dihalocyclopropanes have become readily available and valuable intermediates in organic synthesis[‌252‌–‌254‌] (see also Houben–Weyl, Vol. 4/3, p 150; Vol. E 17a, pp 533, 589; Vol. E 17b, p 1383; and Vol. E 19b, pp 1467, 1521, 1608, 1625), including the preparation of cyclopropane hydrocarbons (one such synthesis is discussed above; see Section ‌48.2.1.2.1‌, ‌Scheme 18‌). After 1954, a considerable variety of methods for the preparation of dihalocyclopropanes ‌163‌ have been developed. All of the practical methods for the in situ generation of a dihalocarbene for subsequent addition to an appropriate alkene rely on α-dehydrohalogenation of chloroform or bromoform.

‌Meeeee 88‌ Mee-Meee Meeeeeeeeeeeeeee ee e Meeeee Meee ee Meeeeeeeeeeee Meeeeeeeeeeee eee Meeeeeeeee Meeeeeeee Meeeeeeeeeeeee ee eee Meeeee[‌888‌–‌888‌]

Me 8888, ee eee eeeee eeee eeee ee α-eeeeeeeeeee eeee eeeeeee eeeeeeeeeeeee eee eeeeeeeeeee ee eeeeeeeee ee e eee-eeeee eeeeee eeeeeeeeee ee eeeeeeeeeeee eeeeeee eeeeee ee eeeeeeeee eeeeeeeee ee e eeee ee eee eeeeeeee ee e eeeeeeeeee eeeeeeee eeee eeeeee ee e eeeee-eeeeeeee eeeeeeee eee eee eeeeeeee ee e eeeeeee ee eee eeeeeeee eee ee eeeee eeeeeee eeee ee eeeeeee.[‌888‌] Meee eeeeeeeee eeeeeeeeeee eee eeeeeeeeeee ee eeeeeeeeeeeeeeeeeee ‌888‌ eeeeeeeeeeee, eee eeeeeeeee eee eeeeee eeeeeeeee e eeeee-eeeeeeee eeeeeeee ee eee eeee eeeeeeeee eeeeeeeeee eee eee eeee eeeeeeeee eee eee eeeeeeeeeeeeeeeeeeeeee ee eeeeeeeeeeeeeeee eeeeeee, eeeeeeeee eeeeeeeeee eeeeeeeee eeeeeee eeee ee ‌888‌ eee ‌888‌ (‌Meeeee 88‌; ee. Meeeeee ‌88.8.8.8.8‌, ‌Meeeee 88‌, eee Meeeeee ‌88.8.8.8.8‌, ‌Meeeee 88‌).[‌888‌,‌888‌,‌888‌,‌888‌–‌888‌] Me e eeeeeeee, eeeeeeeeeeeeeeeeeeeeee eeeeeeee, eeeeeeeeeeeeeeeeee eeeeeeee, ee 88-eeeee-8 eee ee eeee ee eee eeeeeeee ee eeeeeeeeeeeeeeeeeeeeeee; eeeeeee, ee eeeeeeeeee eeeee, eeeee eeeeeeeeee eeeeeeee eeeee (eeeeeeeee eeeeeee-eeeee eeee[‌888‌]) eeee eeeeee eeeeeee.[‌888‌] Me eeeeeeeeeeeeee ee eeee eeeee ee eeeeeee eeeeeeeeee eeee eeeeeeeeeeeeeee, eeeee eeeeeeeee eeeeeeeee (ee eeeeeee ee eeeeee)[‌888‌] eeeeeee ee e eeeeeeeeeeee eeeeeee eeeeeeee eeeee eeeeee eeeeee ee eeeeeeeeeeeeeeeeeeee ‌888‌ (M = Me).

‌Meeeee 88‌ Meeeeeeeeeeeeeeeeeeeee ee Meeeeeeeeeeeeeeeee eee Meeeeeeeeeeeeeeeeeee ee Meeeeeeeeeeee Meeeeeeeeeeeeeeeeee[‌888‌,‌888‌,‌888‌,‌888‌–‌888‌]

‌Meeeeeeeeee 88‌

e Meeeeeeeee eee eeeeeeee.

e MMM eeeeeeee ee e eeeeee.

Mee eeeee eeeeeeee ee eeeeeeeeeeeeeeeeeeeeeee ee eeeeeee eeee eeeeee- eee eeeeeeeee eeeeeeeee eeeee 8888 eeee eeee eeeeeeeee eeeee eeeee-eeeeeeee-eeeeeeeee eeeeeeeeee. Meee, eeeeeeeeeeeeeeeeeeeeeee eeeeeeeeeeeeeeeee ‌888‌, ee eeeeeeee ee eee Meeeeee–Meeee eeeeeeeeeeeeeeee (8% eeeee, Meeeeee ‌88.8.8.8.8‌, ‌Meeeee 88‌), eeeeeeeee eee eeeeeeeeeeeeeee eeeeee ‌888‌ eeeee eeeee-eeeeeeee-eeeeeeeee eeeeeeeeee ee 88% eeeee (‌Meeeee 88‌).[‌888‌] Meee eeeeeee eee eeee eeeeeeee eee eeeeeeeeeeeeeeeee eeeeee (‌888‌, e = 8) ee eeee ‌888‌ (e = 8) eeeeeeee eee eeeeeeee ee Meeeeee eee ee-eeeeeee[‌888‌] (eeeee eeeeeeeee eeee-eeeeeeee),[‌888‌] eeeee eee eeeeee eeee eeeeeeeeee eeeeee eee. Meeeeee, Meeeeee'e eeeeeeeeee eee eeee eeeeeeeee eeee eeeeeeee, eeeeeee eeeee eeeeee eeee eee eeeeee-eeeeeeeee eeeeeee eeee ee ‌888‌ (ee eeee ‌888‌).[‌888‌,‌888‌]

‌Meeeee 88‌ Meeeeeeeeeeeeeeeeeeeee ee Meeeee-Meeeeeeee Meeeeeeeeeeeeeee Meeeeee[‌888‌,‌888‌,‌888‌,‌888‌]

Meeeeeeeeeee, eee ee eeee eeeeeeeeee ee eeeeeeeeeeeeee ee eeeeeee eeeeeeeeeeeee ee (eeeeeeeeeeeeeee)-, (eeeeeeeeeeeeee)-, ee (eeeeeeeeeeeeeeeeeee)(eeeeee)eeeeeee(MM) ee eeeeeee eeeeeee, eeeeeeeee ee Meeeeeee eee ee-eeeeeee,[‌888‌,‌888‌] eee eeee eeeeeeeee eeeeeee ee eee eeeeeeeeee eee eeeeeeeeeeeee eee eee eeeeeeeeeee ee eee-eeeeeeeeeeeeeeeeeee eeee eeee-eeeeeeeee eeeeeee eee eeeeeee ee eee eeeeeeeeee (eee, eee eeeeeee, ‌Meeeee 88‌, M8 = M8 = M8 = M8 = M; M = Me). Meeeeeee, eeeeeee, eeee eeeeee ee eeeeeeeeeee ee eeeeee eeee, ee eeeee eee ee eee eeeeeeeeeee ee eeeeeeeeeeee eeeeeeeeeeee, eeeeeee ee (8) eee eeee eeee eee eeeeeeee ee eeeee eeeeeee eeeeeeeeee, ee eeee ee ee eee eeeeeeee ee eee eeeee eeeeeeee, eee (8) eee eeeeeeee eeee ee eeeeeeeeeeeeeeeee[‌888‌] eeeeeeee ee eee eeeee-eeeeeeee-eeeeeeeee eeeeee.[‌888‌] Mee eeeee eee eeeeeeeee eeeeeeeee eee eeeeeeeeeeeeeee eeeeeeeeee, e.e. eeeeeee eeeeeeeeeeeee ee eeeeee eeeeeeeeeeeeeeee eee eeeeeeee ee eeeee eeeeeeeeeeeeeeee eeee eeeeee eeeeeeeee, ee eeee ee e eee eeee eeeeeee eeeeeee, eeee eeeeee eeee eeee ee eeeeeeeeeee eeeeeeeee, ee ee eee.[‌888‌] M eeeeee ee eeeeeeeeee eeeee eeeeeee eeee eeeeee eeeeeeeeeeee eeeeeee ee eeeeeeeee eeee eeee eeeeeeeeee. Meeeeeeee ee eee eeeee eee,[‌888‌] e eeeeeeeee ee eeeeeeeee ee eeeeeeeee ee eeeeee eeeeeeeeeeee ee eeeeee eeeeeeeeeeeee eeee ee eeee/eeeeee eeeeee ee eeeeeeeeeeee ee eee eeeeeeee ee ee eeeeee. Meeeeee, eee eeeeee ee eeeeeeeeeeeeeeeeeee ee eeeee eeeeeeeeee eee eeee eeeee eeee eeeee eeeeeeee eeee eeeeeeeee eeeee eeeee-eeeeeeee-eeeeeeeee eeeeeeeeee. Me eee eeeeee, eeee eeeeeeeee eeeeeeee, eee eeeeeeeeeeeee eeeeeeeeeee ee eeeeeeeee ee eeeeeeeee eeeeeeee ee eeeeee eeeeeeeeeeeee ee e eee-eeeeee eeeeeeee eeeeeee eeeeeeeee eeee eeeeeeee(MM) eeeeeeee eeee eeeeeeee eeeeeeeee.[‌888‌] Meeeeee, eee eeeee-eeeeeeee-eeeeeeeee eeeeeeeee, eeeee ee eeeeeeeeeee ee eeeeeeeee, ee eeee eeeeeeeee eee eeee eeeeeee eeeeeeeeeeeeee. Meeee eeeee-eeeeeeee-eeeeeeeee eeeeeeeeee, eeeeeeee eeeeeee eeee ee eeeeeeeeee eee eee eeeeeeeee eeeeeee eee eee-eeeeeeeeee eeeeeeeeeeeee eeeeeee ee eeeeeeeee eeeeeeeeeeee eeeeee, eeeee eeeeee eeeeeeee eeeee eee Meeeeee eeeeeeeeee eee eeeeeeee.[‌888‌] Meeeeeee eeeeeeee ee eeeeeeeeeeeeeeeeeeeeeee ee eeeeeeeeee eeeeee eeeee ee eeeeee eeeeeee ‌888‌ ee eeee ‌888‌, eeeeeeeeee ee ‌Meeeee 88‌,[‌888‌,‌888‌–‌888‌] eeeeeee eee eeeeeee eeeeeeeeeee ee eee eeeee-eeeeeeee-eeeeeeeee eeeeeeee.

‌Meeeee 88‌ Meeeeeeee ee Meeeeeeeeeeee[e+8.8.8]eeeeeee Meeee Meeeeeeee Meeeeee ee Meeeeeeeeeeeeeeeeeeeee ee Meeeeee[‌888‌,‌888‌–‌888‌]

‌Meeeeeeeeee 88‌

e MeMM eeeeeeee ee e eeeeee eeeee eeeeeeeeeeeeeee.

Meeeeee eeeeeee eee eeee eeeeeeee ee eee eeeeeeeeeeeeeeee ee eee eeeeeeeeeeeee eeeeeee ‌888‌ (M8 = M, Me) ee eeee ‌888‌ (‌Meeeee 88‌).[‌888‌,‌888‌,‌888‌,‌888‌,‌888‌–‌888‌] Meeeeeee eee eeee eeeeee eee eeeeeeee eeeee eeeeeeeeeeeeeee eeeeeee ee eeeee-eeeeeeee-eeeeeeeee eeeeeeeeee,[‌888‌] eee eeeeeeeeeeeeeee eeeeeeeee eeeeee eeeeee ee eeeeee ee.

‌Meeeee 88‌ Meeeeeeeeeeeeeeeeeeeee ee Meeeeee eee Meeeeeeeeeeeeeeeee eeeee Meeeeee Meeeeeeeee[‌888‌,‌888‌,‌888‌,‌888‌,‌888‌–‌888‌]

‌Meeeeeeeeee 88‌

e MMMM-MMM = eeeeeeeeeeeeeeeeee eeeeeee ee eeee(eeeeeeee eeeeee).

e MeMM eeeeeeee ee e eeeeee eeeee eeeeeeeeeeeeeee.

Mee eeeeeeeee eeeeeee ee eee eee eeeeeeee ee e eeeeeeeeeeeeeeeeee ee eeee eeeeeeeeee eeeeeee eee eeeee eee ee eee eeeeeeee eeeeeeeeeee eeeeeee, eeeeeee eeeeeeee eeeeeee (eeeee eeee eeeeeeeee), eeeeeee (ee eeeeee) ee eeeeee eeeeeee, eeeeeee (ee eeeeee) ee eeeeeeee,[‌888‌,‌888‌] ee eeee ee eeeeee eeee.[‌8‌,‌888‌] M eeeee eeeeeee ee eeeee eeeeeeee eeeeee (ee eeeeee eeeeeeeeee eeee ee eeeeeeeee[‌888‌]) eeee eee e eeeeee eeeeeee eeeeeeeeeee ee eeeeeeeeeee eeeeeeeee. Mee eeeeeee, eee eeee eeeeeeeee eeeeeeeee ee e eeeeeeeeeeeeeeeeee eeee 8 eeeeeeeeeee ee eeeeeeeeeeeeee eeeeeee ee eee eeeeeeee ee 88 eee% eeeeeeee(MM) eeeeeeeeeeee ee eeeeeee eeeee ee eeee eeeeeeeeeee eee eeee eeeeeeee eeee eee e eeeeee eeeeeee [‌888‌ (M8 = Me; M = Me) → ‌888‌ (M8 = Me); ‌Meeeee 88‌], eee eee eeeeeeee eeeeee[‌888‌,‌888‌] ee eee eeeeeee ee eeeeeeeeeeee eeeeeeeee. Mee eeeeee eeeeeeeee eeeeeeeee eeeeeeeeeeeeee ee e eeeeeeeeeeeeeeeeeeee eeee eeeeeeeeeee eeee eeeeeee eeeee ee eee eeeeeeee ee eeeeeeee(MM) eeeeee eee eeeeeeeeeeee ee eeeeeeeeeeeeeee[‌888‌] eeeeeeee ee eeeee e eeeeeeee eeeeee ee eeeeeeeee eeeeeeee(MM) eeeeee ee eeeeeee eeee eeeeee ee eee eeeeeeeeeeee eeeeeeeeeeee. Meeeeee eeeeeeeee eeeeeeeeeeeeee eeeeeeeeeeeeee eeeeeeee, eeee ee eeeeeeeeeeeeeeeeee eeeeeee–eeeeeeeeeee(eeeeeeeeeeeeeeee)eeeeeeee(MM),[‌888‌] eeeeeee eeeeeeee eeeeeee–eeeeeeeee(MM) eeeeeeeeeeeeeee,[‌888‌] eee eeeeeeeeeeeeeee eeeeeeee–eeeeeeeee–eeee(MMM) eeeeeeee[‌888‌] eeee eee eeee eeeeeeee ee eeeeeeeeeeee eeeeeeeeeee eeeeeeeee, eee eeeeeee eeeeeee, eeeeee eeeeeee (ee eeeeee) ee eeeeee eeeeeee eee eeeeeee (ee eeeeee) ee eeeeeeee (Meeeeee'e eeeeeeeeee[‌888‌]) eeee eeee eeee eeee eeeeeeeeee. Meeeee eeeeeeeeeeeeee eeeeeee eeeeeeeeeee eeee eeeeeee eeeeeeeeee; eeeeeee, eee eeeeeeeeeeee ee e eeeee eeeee eee eee eeeeeeeeeee eeeeeeee ee Meeeeee eee ee-eeeeeee eee ee eeee ee eeee. Meeeeeee eee eeee ee eeeeeeeeeeeeee eeeeeee eee eeeee M > Me > Me > M, eeeeeeeeeeeeee ee eeeeeeeeeeeeeeeeeeeee eee eeeeeeeeeeeeeeeeeeee eeeeeee eeee eeeeeee eeeeee (‌Meeeee 88‌).

‌Meeeee 88‌ Meeeeeeee Meeeeeeeeeeeee ee Meeeeeeeeeeeeeeeeee eeeee Meeeeee Meeeeeeeee[‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌]

‌Meeeeeeeeee 88‌

Meeeeeeeeeeee[e+8.8.8]eeeeeee ‌888‌ eee eeeeeee ee eeeeeeee eeee eeeeee eeeeeeeee ee e eeeeeeeeeeeeeeeeeee–eeeeeeee eeee ee eeee eeeeeeee ee eeeeee eeeeeeeeeeee ee eeee ee eeee-eeeeee eeeeeeeee. Meeeeeee eeeeeee ee eeee, eeeee ee ee eeeeeee ee e eeeeeeeeeee ee eeeeeeeeeeeeee ‌888‌ eeee ‌888‌ eeeeeeee Meeeeee'e eeeeeeee. Meeee eeeee eeeeeeee, eeeeeeeeeee eeeeeee, eeeeeee eeeeeeee eeeeeee–eeeeee(M) eeeeeeeeeee, eee eeeeee ee eeeeee eeeeeee eeeeee ee ee eee eeee (‌Meeeee 88‌).[‌888‌,‌888‌–‌888‌] Meee eee eeeeeee eeee eeee MM8 eeeeeeeeee, eeeeeeeeeeeeeeeeeeee ‌888‌ eeeee eeee eeeeeee eeeeeeee eeeeeee eeeeee eeeeee; eeeeeee, eeeeeeee ee eeeeee(M) eeeeeeeeeee (8 eee%) eeeeeeeeeee eeeeeeeeeee eeee eeeeeeeee eee eeeee ee eeeeeeeeeeeee eeeeeeee[‌888‌] (eeeeeeeeeeeee, eee eeeeeeeeeee[‌888‌] eeee eee eeeeeee e eeee eeeeeeeeeeee eeeeeeeee eee eeeee eeeeeeeeeeee). ‌Meeeee 88‌ eeeeeeeeeeee eeee eee eeeeee ee eeeeeee[e+8.8.8]eeeeeee ‌888‌ eeeeee eeeeee 88%, eeeee eee eeeeeeeeeee eeeeeeeeeee ‌888‌ ee eeeeeeee ee eeeeee eeeeeeeeeeee eeeee (‌Meeeee 88‌).[‌888‌]

‌Meeeee 88‌ Meeeeeeee ee Meeeeee[e+8.8.8]eeeeeee ee Meeeeeeee Meeeeeeeeeeeee ee Meeeeeeeeeeeeeeeeee[‌888‌,‌888‌–‌888‌]

‌Meeeeeeeeee 88‌

‌Meeeee 88‌ Meeeeeeee ee Meeeeee[8.8.8.8]eeeeeeeee ee Meeeeeeee Meeeeeeeeeeeee ee e Meeeeeeeeeeeeeeeee[‌888‌]

‌Meeee 8‌ eeeeeeeeee eeee ee eee eeee eeeeeee eee eee-eeee (Meeeeee–Meeee[‌888‌,‌888‌,‌888‌,‌888‌]) eee eee-eeee eeeeeeeeeeeeeeeee (eeeeeeeeeeeee eeeeeeeeeeeee[‌888‌,‌888‌,‌888‌,‌888‌] eee eeeeeeeee eeeeeeeeeeeeee[‌888‌,‌888‌,‌888‌,‌888‌]) eee eeeeeee eeeeeee eeeeeeee eeee eeeeeeee eeeeeee.

‌Meeee 8‌ Meeeeeeeee ee Meeeeeee Meeeeeeeee ee Mee-Meee Meeeeeeeeeeeeeeee eeee eeeee ee e Meeeeee–Meeee Meeeeeee[‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌]

Meeeee	Meeee (%) eee MM8 Meeeeeee	Meeee (%) eee Meeeeeeee Meeeeeeeeeeeee	Meeeeee Meeee (%)	Meeee (%) eee Meeeee Meeeeeeeeeeeeeee	Mee
	88 (M = Me)	88	88	88	[‌888‌,‌888‌,‌888‌]
	88 (M = Me)	88	88	88	[‌888‌,‌888‌,‌888‌]
	88 (M = Me)	88	88	88	[‌888‌,‌888‌,‌888‌]
	88 (M = Me)	88	88	88	[‌888‌,‌888‌,‌888‌]

Me eee eeee eeeeee eeee “eee eeeeeeee ee e eeeeeeeeeeeee ee ee eeeeee eee eeeeeeeeee eeeeeeeeeeeeee ee eee eee-eeeeeeeeeeeeeeeeee eeeeee eeee … e eeeeeeeeee eeeeeeeeeeeee eeeeeeeeeeee eeeeeeeeee ee, ee e eeee, e eeee eeeeeeeee eee eeeeee eeeeee eee eee eeeeeeeeeee ee eeeee eeeeeee ee eeeeeeeee eeee ee eeeee eeeeee eeeeeeeee … ee eee Meeeeee–Meeee eeeeeeeeeeeeeeee ee ee eeeeee”.[‌888‌] Meeeeee, ee eee eeeeeeee ee ‌Meeee 8‌ eeeeeeeeeee, eeee eeeeeeeee eeeee eee eeeeeeee eeeee eeee. Meeeee, eee eee-eeee eeeeeeeeeeeeeeee ee ee eeeeee ee eeeeeeeeee eee eeeee eeee ee eee eeeeeeeee:

(8) Me eeeeee e eeeeeee eeeeeeeeeeeee ee eee eeeeeeeeeeee eeeeeeeeee, eee eeeeeeeee eeeeeeeeeeeeeeeeeeee ee eee eeeeeee eeeeeeeeeeeeee eee ee eeeeeeeee (eee, eee eeeeeee, eee eeeeeeeeeee ee eeeeeeeee eeeeeeeeeeeee ee eeeeeeeeeeeeeeeeeeeeeeeee[‌888‌]).

(8) M eeeeee ee eeeeeeeeee eeeeeeeee, eeeeeee eeeeeeeeeeeeeeee, eeeeeee ee eee eeeee eeee eee eeee ee Meeeeee–Meeee eeeeeee ee eee, ee eeeeeee eeeeeeeeeeeee ee eeee eee eeeee (ee. Meeeeee ‌88.8.8.8.8‌, ‌Meeeee 88‌). Me eeee e eeee, eee eee-eeee eeeeeeeeeeeeeeee eeeeeee eee eeee eeeeeeee eeeeee, ee eeeee ee eee eeeeeeeeeee eeeeeeee eeeeee. M eeeeeeeee eeeeeee ee eeee e eeeeeeeee ee eee eeeeeeeeeeeeeeee ee eee eeeeeeeeeeeeee eeeeeeeeeeeeeeeeeee eee- eee eeee-‌888‌ (‌Meeeee 88‌). Meee, eee-‌888‌ eee ee eeeeeeeeeee eeee eee-‌888‌ eeeee e eee- ee e eee-eeee eeeeeeeee ee 88 eee 88% eeeeeee eeeeee, eeeeeeeeeeee.[‌888‌] Me eeeeeeee ee eeee, eeee-‌888‌ eeee eeeeeee eeeeeeeee eee eeeeeeeeeeeeee,[‌888‌] eee eeeeeeeee eee eeeeeeeeeeeeeee eeeeee eeee-‌888‌ ee 88% eeeee. Meeeeeeeee eeeeeeeee eeeeeeeeeeeeee ee eeee-‌888‌ eeeeeee eeee-‌888‌ ee 88% eeeeeee eeeee.[‌888‌] Meeeeeeee eeeeeeeeeeeeee ee eee eee(eeeee)eeeeeeeee eeeeeeee eee-‌888‌ eee eee eeee eeeeeeee.[‌888‌] Meeeeeeee, 8,8-eeeeeeeeeee-8-eee (‌888‌) eee eeee ee eeeeeeeeeeeeeee ee eeeee e eee-eeee eeeeeeeee.[‌888‌]

‌Meeeee 88‌ Mee- eee Mee-Meee Meeeeeeeeeeeeeeee ee Meeeeeeeeee Meeeeeeeeeeeeeeeeee eee 8,8-Meeeeeeeeee-8-eee[‌888‌–‌888‌]

Mee eeeeeeeeeeee ee eeeeeeeeee eeeeeeeee eeeeee eee eeeeeeee eeeeeeeeeeee ee eeeeeeeeeeeeeeee ee eeeeeeeeee eeeeeeeeeeeeeeeeeee eee eeeeeeee eee eeee eeeeeeeeeee eeeeeeee eee eee eeeeeeeeeee ee e eee-eeee eeeeeeeeeeeeeeee eeeeeeee. Meee, eeeeeeeeeeeeeeeeeeeeeeeeeee eee eee eeeeeeeeeeeeeeeeeeee eeeeeeee ‌888‌ ee eee eeeeeee eeeeeeeeeeeeeeee eeee eeeeeeeee eeee eee Meeeeee–Meeee eeeeeee ee eeee eeeeeeeeeeee–eeeeeeeee(MM) eeeeeee ee eee, eeeee eeeeeeeeeeeee eeeeeeeeeeeeeeeeee eeeeee eeeee [8]eeeeeeeeeee (eeeeeee[8.8.8.8]eeeeeee, ‌888‌) ee eee eeeee (8–88%). Meeeeee, ee eeeeee eeeeeeeeeeeeeeeeee ee eeee ee eeeeeeeeee ‌888‌ eee eeeeeeeeeeeeeeeeeeeeeeeeeee eee ee eeeeeeeee eeee eee eeeeeeeeeeeee eeeeeeeeeeeeeeeeeeee ‌888‌, ‌888‌, eee ‌888‌ ee 88, 88, eee 88% eeeeee, eeeeeeeeeeee (‌Meeeee 88‌). Meeeeeeee eeeeeeeeeeeeee ee eeeee eeeeeeeee eeeeeee eee eeeeeeeeeeeee eeeeeeeeeeee ee 88–88% eeeee, e.e. ‌888‌ eeeee ‌888‌ eee ‌888‌ eeeeee eee M8e-[88]eeeeeeeeeee ‌888‌, eee eeeeeee eeeeeeee eeeeeeeeeee eeeee ee ee eee.[‌888‌] Meee eeeeeee eee ee eeeeeee eeeeeeeeeee, eee eeeeeeeee eeeeeeeeeeeeee eee ee eeeeeeeeeee ee eeee eeeeeee ee eee eeeeeeeeeeeeeeeeeeeeee eeeeeeee, eeeeeee, eee eeeeeee, ee ‌888‌ eeee ‌888‌;[‌888‌] eeeeeee, ee eeeee eeeeeeeeeee, [8]eeeeeeeeeee (eeeeeee[8.8.8.8]eeeeeee, ‌888‌) ee eeeeeeee eeeeeeeeeee eeee ‌888‌ eeeee eee eeee eeeeeeee eeeeeeeeee.[‌888‌]

‌Meeeee 88‌ Meeeeeeee ee Meeeeeeeee Meeeeeeee Meeeeeeeeeee ee eeee ee [8]Meeeeeeeeee[‌888‌,‌888‌,‌888‌]

(8) Me eeeeeee eeeee e eee-eeee eeeeeeeeeeeeeeee eeeeeeeee eee eeee eeee ee eeeeeee eeeeeeeeeeeee eeeeeee eeee eeeeeeeee, e.e. eeee- eee eee-‌888‌ eeee eeee- eee eee-‌888‌ (‌Meeeee 88‌).[‌888‌] Meee ee e eeee eeeeeeeee eeeeeeeeeee ee e Meeeeee–Meeee eeeeeeeeeeeeeeee eeeeeeeee eeeeeeeeeeeeeeeeeeeeee.[‌888‌] Mee eeeeeeeeeeee eeeeeeeeeee[8.8]eeeeeee ‌888‌ eee eeee ee eeeeeeee ee eeeeeeeeeeee eeeeeeeee.[‌888‌]

‌Meeeee 88‌ Meeeeeeee ee Meeeeeeeee eee Meeeeeeeeeeee Meeeeeeeeeeeee Meeeeeeeeeeeeeeeeee[‌888‌]

Meeeeeeeeeee Meeeeeeee

8,8-Meeeeeeeeeeeeee[8.8.8.8]eeeeeee (‌888‌, M8 = M8 = M8 = M8 = M; M = Me); Meeeeee Meeeeeeee:[‌888‌]

Me e eeeeeeeeee eeeeeee eeee ee eeeeeeeeeeeeeeeeee (‌888‌, M8 = M8 = M8 = M8 = M; 8.88 e, 88.8 eeee) eee MMMMM (888 ee, 8.88 eeee) ee e eeeeeee ee MMMe8 (88 eM), eeeeeee (88 eM), eee MeMM (8.8 eM) eee eeeee eeeeeeee 88% ee MeMM (88 eM). Meeee eeeeeeee eeeeeeee ee ee eee ee eeeeeeeeee 8 e, eee eeeeeee eeeee eee eeeeeeeee, eee eee eeeeeeeee eeeee eee eeeeeeeee eeee MM8Me8 (8 × 88 eM). Mee eeeeeeee eeeeeeee eeee eeeeee eeee M8M (88 eM), eeeee (MeMM8), eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeee eee eeeee ee eeee eeeeeee (88 eM), eee eee eeeeeee eee eeeeeeee eeeeeee e eee ee eeeeee eee, eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee eeeee. Meeeeeeeeee ee eee eeeeeee ee 88°M/88 Meee eeee eeeeeeeee eeeeeeee ee eee eeeeeee; eeeee: 8.88 e (88%); ee 88°M; 8M MMM (MMMe8, δ): 8.88–8.88 (e MM′MM′, 8M).

88,88-Meeeeeeeeeeeeeeee[8.8.8.8.8.8.8.8]eeeeeeee [‌888‌, M8 = M8 = M; M8,M8 = (MM8)8; M = Me]; Meeeeee Meeeeeeee:[‌888‌]

MMMMMMM: Meeeeeeeeeeeeeeeeeeeeeee eeee eeeeeeee eeeeeeeee eeeeeeeee eee eeeeeee eeee eeeeeeeee. Meee eeeeee ee eeeee ee eeeeeee eee eeeeeeee eeeeeeeeeee eeeeee eee eeeee 8–8 eeeee.

Meeeeeee MMM (88.88 e, 888.8 eeee) eee eeeee ee eee eeeeeee ee −88°M ee e eeeeeeeeee eeeeeee eeee ee eeeeee ‌888‌ [M8 = M8 = M; M8,M8 = (MM8)8; 8.888 e, 88.88 eeee], MMMe8 (88.88 e, 88.8 eeee), eee MMMMM (888.8 ee, 8.88 eeee) ee MM8Me8 (88 eM). Mee eeeeeeeeee eeeeeeee eee ee ee 8°M. Mee eeeeeeeeeee ee eee eeeeeee eee eeeeeeeeee ee 8–88°M ee eeeeeeee eeeeeee eee eee eeeee 8.8 e, eeee eee eeeeeee eee eeeeeeeeee eeeeeee ee ee eee ee eeeeeeeeee 8 e, eeeeeee eeee eeeeeee (88 eM) eee, eeeee eeeeeeee ee ee eee 8 e, eeeeeeee eeeeeee e 8-ee eee ee eee eeee. Meeee eeeeeeeeeeeee eeeee eeeeeee eeeeeeee, eee eeeeeee eee eeeeeeeeeeeeee (MeMM) ee −88°M eee eeee eeeeeeee ee 88°M/8.8 Meee ee eeee eee eeeeeee ee e eeeee eeeeee eeeee; eeeee: 8.88 e (88%); ee 88–88°M; 8M MMM (MMMe8, δ): 8.88 (eee, 8M, M = 8.8, 8.8, 8.8 Me), 8.88 (e, 8M), 8.88 (eee, 8M, M = 8.8, 8.8, 8.8 Me), 8.88 eee 8.88 (e, 8M, MM′MM′), 8.88 (eee, 8M, M = 8.8, 8.8, 8.8 Me); 88M MMM (MMMe8, δ): 8.8 (8MM8), 8.8 (8MM8), 8.8 (8MM8), 88.8 (8M), 88.8 (M), 88.8 (M), 88.8 (M).

8,8-Meeeeeeeeeeeee[8.8.8.8]eeeeee (‌888‌, e = 8; M = Me); Meeeeee Meeeeeeee:[‌888‌]

M eeeeeee ee eeeeeeeeeeeeeeeee (‌888‌, e = 8; 8.88 e, 88 eeee), e-MeMM (8.88 e, 88 eeee), eee eeeee eeeeeeeee eeeee (888 eM) eee eeeeeee ee 8°M eee 88 eee eeeee ee eeeeeeeeee ee M8. M eeee ee MMMe8 (8.88 e, 88 eeee) ee eeeee eeeeeeeee eeeee (8 eM) eee eeeee eeeeeeee eeee e eeeeee ee 88 eee. Mee eeeeeee eee eeee eeeeeee ee eeee ee ee eee eeeeeee eee ee eeeeeeeeee 88 e. Mee eeeeeeeee eeeeeeee eee eeee eeeeeee ee eeeeeeeeee, eee eee eeeeeeeeeee eee eeeeee eeee eeeeeeeee eeeee (88 eM). Mee eeeeeeee eeeeeee eeeeee eeee eeee eeeeeeeeeeee eeeee eeeeeee eeeeeeee ee 8°M ee eeee e eeeee, eeeeeeeeeee eeeee eeeeeee (8.88 e). Meeeee eeeeeeeeeeeeee (eeeeee eee, eeeeeeeee eeeee) eeeeeeee e eeeeeeeee eeeee; eeeee: 8.88 e (88%); ee 88–88°M; MM (MMe) ν̃eee: 8888, 8888, 8888 ee−8; 8M MMM (MMMe8, δ): 8.88–8.88 (e, 88M).

8,8-Meeeeeeeeeeeeee[8.8.8]eeeeeee (‌888‌, e = 8; M = Me; 8,8-Meeeeeeeeeeeeeeee); Meeeeee Meeeeeeee Meeee e Meeeeeeee Meeeeeee:[‌888‌]

Me e eeeeeeeeee ee Me eeeeee (888 ee, 88 eeee), MeMe8 (888 ee, 8 eeee), eeeeeeeeeee (888 ee, 88 eeee), MMe8 (8.88 e, 88 eeee) (MMMMMMM: eeeee), eee 8,8-eeeeeeeeeeeeee (88 eM) eee eeeee ee 8°M, eeee eeeeeeee, MMM (8.8 eM) ee eee eeeeeee. Mee eeeeeee eee eeeeeee ee 8°M eee ee eeeeeeeeee 8 e, eeee eee. ee M8MM8 (88 eM) eee eeeee, eee eee eeeeeee eee eeeeeee eeee Me8M (88 eM). Mee eeeeeee eeeee eee eeeeeeeee, eeeee (MeMM8), eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeee eeeeeeeeeeeeee (eeeeee eee, eeeeee) eeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 8.88 e (88%); 8M MMM (MMMe8, δ): 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M); 88M MMM (MMMe8, δ): 88.8 (8MM), 88.8 (8MM8), 88.8 (8MM8), 88.8 (M).

8,8-Meeeeeeeeeeeeee[8.8.8]eeeeeee (‌888‌, e = 8; M = Me; 8,8-Meeeeeeeeeeeeeeee); Meeeeee Meeeeeeee Meeee Meeeeeee'e Meeeeeee:[‌888‌]

MMMMMMM: Mee eeeeeeeeee eeee eeeee (eeeeeeeeeeeeeeeeeee)(eeeeee)eeeeeee(MM) eee eeeeeeeeeeeee eeeeeee eeeeee ee eeeeeeeee ee e eeee-eeeeeeeeee eeee; eeee eee eeee eeeeee ee eeee eeeeeeeee.

Meee eeeeeeeee ee eeeeeee eeee eeee eee eeeeee eee eee eeeeeeeeeeee eeeeeee eee eeeeeee. Me e 888-eM eeeee eeeeeeee eeee e eeeeee eeeeeeeee eee eeeeeeee eeeeeeee eee eeee eeeeee MeMeMMeMe8 (88.88 e, 88 eeee), eeeeeeeeeee (8.88 e, 88 eeee), eee eeeeeee (88 eM) (MMMMMMM: eeeeeeeeee). Mee ee eee eeeeeee eeeeeee eee eeeeeeeee ee eee eeee eee eeeeee eeeeeeeeeee eee eeeeeee; eeeeee 88 eee, eeeeeeeeeeeee ee e eeeeeeeee, eeeee eeeee eeeee. Meeee eee eeeeeee eee eeee eeeeeee ee eeeeee eee ee eeeeeeeeee 8 e, ee eee eeeeee eee eeeeeeee, eeeeeee MeMeMe [88.8 e (88%)]. Mee eeeeeee eee eeeeee eeeeeeeeeee eeee eeeeeee ee eeee-ee-eeee eeeeeeeeeeee ee 88°M/8 Meee eee eee eeeeeee eee eeee-ee-eeee eeeeeeeee eeeeeee ee 88°M/8.88 Meee eeee e eeeeeeee eeeeee ee −88°M. Mee eeeeeeeeee eee eeeeeeeeeeee eeeeeeeee ee eeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 8.88 e (88%); ee 88–88°M/88 Meee.

8,8-Meeeeeeeeeeeee[8.e.8]eeeeee (‌888‌, e = 8; M = Me); Meeeeee Meeeeeeee Meeee eee Meeee-Meeeeeee-Meeeeeeee Meeeeeee:[‌888‌]

M eeeeeee ee eeeeeeeeeee (‌888‌, e = 8; 88.8 e, 888 eeee), MMMe8 (888.8 e, 888 eeee), MM8Me8 (88 eM), MeMM (8 eM), MMMMM (888 ee, 8.8 eeee), eee 88% ee MeMM (888 e, 8.8 eee) eee eeeeeeeeee eeeeeee eee 8 e, eeeeeeeeeee eee eeeeeeeeeee ee 88–88°M ee eeeeeeee eeeeeee. Meeee eee eeeeeeeeee eeeeeeee eee eeeeee, eee eeeeeee eee eeeeeee ee ee eee ee eeeeeeeeee 8 e, eee eeee eeeeeee eeee eee-eeee M8M (888 eM). Mee eeeeeee eeeee eee eeeeeeeee eee eee eeeeeeeee eeeee eee eeeeeeeee eeee MM8Me8 (8 × 888 eM). Mee eeeeeeee eeeeeeee eeee eeeeee eeee 8% ee MMe (88 eM) eee M8M (88 eM), eeeee (MeMM8), eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeeeeeeeee eeeee eeeeeee eeeeeeee eeee eee eeeeeee ee e eeeee eeeeee eee; eeeee: 88.8 e (88%); ee 88–88°M/8.88 Meee; MM (eeee) ν̃eee: 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 888, 888, 888, 888, 888, 888 ee−8; 8M MMM (MMMe8, δ): 8.88 (e, 8M), 8.88–8.88 (e, 88M), 8.88 (e, 8M); 88M MMM (MMMe8, δ): 88.8 (8MM), 88.8 (8MM8), 88.8 (8MM8), 88.8 (8MM8), 88.8 (M).

8,8-Meeeeeee-8-eeeeeeeeeeeeeeeeee (‌888‌, M8 = M; M = Me); Meeeeee Meeeeeeee Meeeeeeee Meeeeeeeeeeeeee:[‌888‌]

M 888-eM, eeeee-eeeeee, eeeee-eeeeeeee eeeee eeeeeeee eeee e eeeeeeeeee eeeeeee (eeeeeeee 8-ee eeeeee Meeeee eeeee) eee eeeeeee eeee e eeeeeee ee eeeeeeee MeMM (888 ee, 88 eeee) eee e eeee ee eeeeeee (888 ee, 8.8 eeee) ee MMMe8 (88 eM). Mee eeeee eee eeeeeeee ee ee eeeeeeeeee eeeeeeee eeee eee eee eeeeeeeeee eeeeeeeeeeeee 8 ee eeeee eee eeeeee ee eee eeee. Mee eeeeeee eee eeee eeeeeeeeeeeeee eeeeeee eee eeeeeeeee ee eeeeeeeeeeeeeee eee 8 e (eee eeeeeeeeeee ee eee eeee eeeee eeeeeeee 88°M). Meeeeeee ee eee eeeeee eeeee (MM) eeeeeeeee eeeeeeee eeeeeeeeeeeee ee eee eeeeeee. Mee eeeeeeee eeee eeee eeeeeeeeeee, eee eee eeeeeee eeeee eee eeeeeeeee. Meeee eee eeeeee MMMe8 eee eeee eeeeeee eeeee eeeeeee eeeeeeee, eee eeeeeee eee eeeee ee eeee Me8M (88 eM), eeeeee eeee M8M (8 eM), eeeee (MeMM8), eee eeeeeeeee (Meeeeeeee) ee 88°M/8.8 Meee ee eeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 888 ee (88%); 8M MMM (MMMe8, δ): 8.88 (e, 8M, M = 8.8 Me), 8.88 (ee, 8M, M = 88.8, 8.8 Me), 8.88 (ee, 8M, M = 88.8, 8.8 Me), 8.88–8.88 (e, 8M); 88M MMM (MMMe8, δ): 88.8 (MM8), 88.8 (MM), 88.8 (M), 888.8 (8MM), 888.8 (8MM), 888.8 (MM), 888.8 (M).

8,8-Meeeeee-8-eeeeee-8-eeeeeeeeeeeeeeeeee (‌888‌, M8 = Me; M = Me); Meeeeee Meeeeeeee Meeee ee Meee/Meeeee Meeeee:[‌888‌]

M eeee ee MMe8 (8.88 eM, 8.88 e, 88 eeee) ee MeMM (8 eM) eee eeeee ee e eeee-eeeeeee eeeeeee ee Me eeeeee (8.88 e, 888 eeee), Me eeeeee (8.88 e, 888 eeee), eee eeeeeee ‌888‌ (M8 = Me; 8.88 eM, 8.88 e, 88.8 eeee) ee MeMM (88 eM); eee eeeeeeeee eeeeeee eee eeeeeee ee 88°M eee 8 e. Meeee eeeeeee ee ee, eee eeeeeee eee eeeeeeee, eee eee eeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeee eee eeeee ee eeee eeeeeee (88 eM), eee eee eeee eee eeeeeeee eeeeeee e eee ee eeeeee eee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee eeeee. Meeeee eeeeeeeeeeeeee ee eee eeeeeee (eeeeee eee, eeeeee) eeee eee eeeeeee ee e eeeeeeeee eee; eeeee: 8.88 e (88%).

8-Meeeee-8-eeeeeeeeeeeeeeeeee (‌888‌, M8 = Me); Meeeeee Meeeeeeee Meeee Meeeeee'e Meeeeeee:[‌888‌]

Meeee ee eee eeee (88–888°M), e eeee ee eee eeeeeeee ‌888‌ (M8 = Me; M = Me; 88.8 e, 8.88 eee) ee MeMM (888 eM) eee eeeeee ee eeeeee eeeee M8 ee e 8-M eeeee-eeeeeeee eeeee eeeeeeee eeee e eeeeeeeeee eeeeeee eee eeeeee eeeeeeeee. Me (88.8 e, 8.88 eee) eee eeeee ee eeeee eeeeeeee ee eeee eeeeeeeeeee, eeee eeeeeeee, eeee e eeeeee ee 8 e. Me eee eee ee eee eeeeeeee eee eeee eeeeeeeeeee eee eeeeee ee 888°M eee ee eeeeeeeeee 8.8 e. Meeee eeeeeee ee ee, MeMM (888 eM) eee eeee M8M (888 eM) eeee eeeee, eeee eeeee eeeeeee, ee eeeeeee eee eeeeeeeee Me, eee eee eeeeeee eee eeeeeeeee eeee eeeeeeeee eeeee (ee 88–88°M; 8 × 888 eM). Mee eeeeeeee eeeeeeee eeee eeeeee eeee M8M (888 eM), 88% ee MeMM (888 eM), eee eeeee (888 eM), eeeee (MeMM8), eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeeeeeeeee eeeee eeeeeee eeeeeeee ee eee eeeeeeee eeee eeeeee eee (88.8 e) eeeeeeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 88.8 e (88%); ee 88°M/88 Meee; 8M MMM (MMMe8, δ): 8.88 (e, 8M, eeeeeeeeeee-M), 8.88 (e, 8M, eeeeeeeeeee-M), 8.88 (e, 8M, Me), 8.88 (e, 8M, eeee-M); 88M MMM (MMMe8, δ): 88.8 (8MM8), 88.8 (M), 88.8 (MM8), 888.8 (MM), 888.8 (8MM), 888.8 (8MM), 888.8 (M).

Meeeeeeeeeeeeeeeee (‌888‌, M8 = M); Meeeeee Meeeeeeee Meeee Meeeeeeee'e Meeeeeee:[‌888‌]

Me e eeee ee eee eeeeeeee ‌888‌ (M8 = M; M = Me; 888 ee, 8.8 eeee) eee Me(Me)8Me8 (88 ee, 8.88 eeee) ee eeeee 8,8-eeeeeee (88 eM) eee eeeee, eeeeeeee, e 8.88 M eeee ee MMMMM-M ee eeeeee (8.8 eM, 88 eeee), eee eee eeeeeee eee eeeeeee ee 88°M eee 8 e. Meeee eeeeeee ee 8°M eee eeeeeee eee eeeeee eeeeee eeee eee-eeee 88% ee MMe; eee eeeeeeeee eeeeeee eee eeeeeee eee 88 eee, eee eee eeeeeee eeeee eee eeeeeeeee eeee eeeeeee (8 × 88 eM). Mee eeeeeeee eeeeeeee eeee eeeeee eeee eee. ee MeMMM8 (88 eM) eee M8M (88 eM), eeeee (MeMM8), eee eeeeeeeeeeee ee eeeeeee eeeeeeee. Meeeee eeeeeeeeeeeeee ee eee eeeeeee (eeeeee eee, eeeeeee) eeee eee eeeeeee ee e eeeeeeeee eee; eeeee: 888 ee (88%); MM (eeee) ν̃eee: 8888, 8888, 8888, 8888, 888, 888 ee−8; 8M MMM (MMMe8, δ): 8.88 (e, 8M, eeeeeeeeeee-M), 8.88 (e, 8M, eeeeeeeeeee-M), 8.88 (ee, 8M, M = 8.8, 8.8 Me, eeeeeeeeeee-M), 8.88–8.88 (e, 8M, eeee-M); 88M MMM (MMMe8, δ): 8.8 (8MM8), 88.8 (MM), 888.8 (MM), 888.8 (8MM), 888.8 (8MM), 888.8 (M).

eee-Meeeeee[8.8.8]eeeeee (‌888‌, e = 8); Meeeeee Meeeeeeee Meeee Meeeeeeeeee Meeeeee:[‌888‌]

MMMMMMM: Mee eeeeeeeeee eeee eeeee eeeeeeeeeee eeeeeee eeeeee ee eeeeeeeee ee e eeee-eeeeeeeeee eeee; eeee eee eeee eeeeee ee eeee eeeeeeeee.

Me8MeM (88.88 e, 888 eeee) eee eeeee eeeeeeee eeee 8 e ee e eeeeeee eeee ee eeeeeeee ‌888‌ (e = 8; M = Me; 88.88 e, 88 eeee) ee eeeee Me8M (88 eM), eeeeeeeeeee eee eeeeeeeeeee eeeeee eee eeeee ee 88–88°M. Meeee eeeeeeee ee eee eeee eeeeeeeeeee eee ee eeeeeeeeee 8 e, eee eeee eeeeeeee eeeeeeeeee ee eee eeeeeee eeee eeee-ee-eeee eeeeeeeee eeee e eeee (−88°M) eeee ee 88°M/8 Meee. Mee eeeeeeee ee eee eeee eeee eeeeeeeee eeeee eeeeeee eeeeeeee ee eeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 8.88 e (88%); ee 88°M/88 Meee; 8M MMM (MMMe8, δ): −8.88 (e, 8M), 8.88 (e, 8M), 8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88 (e, 8M); 88M MMM (MMMe8, δ): 8.8 (MM8), 88.8 (8M), 88.8 (8MM8), 88.8 (8MM8), 88.8 (8MM8). Mee eeeee eee eeeeeeee ee eeeeeeee ee eeeeee Me8M (8.8 eeeee eeee eeeeeee ee Me8MeM; e eeeeeeee eeeeeeee eee eee eeee eeeeeeee[‌888‌]).

eee-Meeeeee[8.8.8]eeeeee (‌888‌, e = 8); Meeeeee Meeeeeeee Meeee Meeeee ee Meeeee Meeeeee:[‌888‌]

Me (8.88 e, 8.888 e-ee) eee eeeeeeeee ee eeeee eee MM8 (888 eM) ee −88°M; ee eeee eeee eee eeeee, eeeeeeee, e eeee ee eeeeeeee ‌888‌ (e = 8; M = Me; 8.88 e, 88 eeee) ee eeeee Me8M (88 eM) ee eee eeee eeeeeeeeeee eeee e eeeeee ee 88 eee. Meeee eeeeeeee ee eeee eeeeeeeeeee eee ee eeeeeeeeee 88 eee, eee eeeeeee eee eeeeeeeee eeeeeee eeee eeeeeeee MM8Me (8.88 e, 88 eeee). Mee eeeeee MM8 eee eeeeee eeeeeeeeee eeeeeee e eeee eeee (−88°M, 8,8-eeeeeeeeeeeeee/eee eee); eeeeeee (88 eM) eee eee-eeee M8M (888 eM) eeee eeee eeeee. Mee eeeeee eeee eeeeeeeee eee eee eeeeeee eeeee eee eeeeeeeee eeee eeeeeee (8 × 88 eM). Mee eeeeeeee eeeeeeee eeee eeeeee eeee eee. ee MM8Me (88 eM) eee eeeee (88 eM), eeeee (MeMM8), eee eeeeeeeeeeee ee eeeeeee eeeeeeee. Meeeeeeeeeee ee eee eeeeeee eeeee eeeeeee eeeeeeee eeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 8.88 e (88%); ee 88–88°M/88 Meee; eeeeee 88.8% (MM).

8,8,8,8,8,8,8,8-Meeeeeeeeeeeeeeee[8.8.8.8]eeeeeee (‌888‌); Meeeeee Meeeeeeee:[‌888‌]

Meeee ee eeeeeeeeee ee eeeee, Me eeeeee (88.8 ee, 8.88 ee-ee) eee eeeee ee e eeeeeeeeee eeeeeee eeee ee eeeeeeeeee ‌888‌ (888 ee, 8.888 eeee) eee e-MeMM (888 μM, 8.88 eeee) ee eeeee MMM (88 eM). Mee eeeeeee eee eeeeeee ee ee eee 88 e, eeee eeeeee eeee eee-eeee M8M (88 eM), eee eeeeeeeee eeee MM8Me8 (8 × 88 eM). Mee eeeeeeee eeeeeeee eeee eeeee (MeMM8) eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeeee eeeeee eeee eeeee ee eeee eeeeee (88 eM), eee eeeeeee eee eeeeeeee eeeeeee e eee ee eeeeee eee, eee eee eeee eee eeeeeeeeeeee eeeee. Mee eeeeeee eee eeeeeeeeeeeeee (eeeeee, eeeeeee eeeeeeee) ee eeee ‌888‌ ee eeeeeeeee eeeeeeee; eeeee: 88.8 ee (88%); ee 88–88°M; 8M MMM (MMMe8, δ): 8.88 (e, 8M, eeeeeeeeeee-M), 8.88 (e, 88M, 8MM8); 88M MMM (MMMe8, δ): 8.8 (MM8), 88.8 (8MM8), 88.8 (8MM8), 88.8 (8M), 88.8 (8M).

eeee-8,8-Meeeeeeee-8-eeeeeeeeeee[8.8]eeeeeee (eeee-‌888‌); Meeeeee Meeeeeeee:[‌888‌]

Me e eeee-eeeeeee eeeeeeeeee ee Me eeee (8.888 e, 88 e-ee) ee MM8MM (88 eM) eee eeeee e eeeee MMe eeee (eee eeeee) ee ee; eeeee eeeeeeee eee ee eeeeeeeeee 88 eee, e eeee ee eee eeeeeeeee eeee-‌888‌ (8.88 e, 88 eeee) ee MM8MM (8 eM) eee eeeee eeeeeeee. Mee eeeeeee eee eeeeeeeeee eeeeeee ee ee, eeeeeeeeee eee eeeeeeee ee eee eeeeeeee ee MM. Meeee 8 e, eee eeeeee Me eee eeeeeee ee eeeeeeeeee, eee eeeeeeee eee eeeeeee eeee M8M (88 eM) eee eeeeeeeee eeee Me8M (8 × 88 eM). Mee eeeeeeee eeeeeeee eeee eeeee (MeMM8) eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeeeeeeeee ee eee eeeeeee eeeee eeeeeee eeeeeeee eeee eee eeeeeee ee e eeeeeeeee eeeeee; eeeee: 8.88 e (88%); eeeeee 88% (MM); ee 88–88°M/88 Meee; eeeeeeeee eeeeeee ≥88%; 8M MMM (MMMe8, δ): 8.88 (e, 8M), 8.88 (ee, 8M, M = 8.8, 8.8 Me), 8.88 (ee, 8M, M = 8.8, 8.8 Me), 8.88 (ee, 8M, M = 8.8, 8.8 Me), 8.88–8.88 (e, 8M, eeee-M).

8-Meeeeeeeeee[8.8]eeeeeee (‌888‌); Meeeeee Meeeeeeee:[‌888‌]

MMMMMMM: Meeee eeeeeee eeeeeeee eeeeeee eeeeee eeeeeeeeee eeee e eeeeeee ee eeeeeeeeee, eee eee eeeeee ee eeeeeee ee eeeeeeee eeeeeeee.

Me e eeeeeee eeee ee MeMeM8 (888 ee, 8 eeee) ee eeeee Me8M (88 eM) eee eeeee eeeeeeee e eeee ee eeeeeeeee eeee-‌888‌ (8.88 e, 88 eeee) ee Me8M (8 eM), eeeeeeeeeee eee eeeeeeeeeee ee 88–88°M. Mee eeeeeee eee eeeeeeeeee eeeeeee ee ee eee 88 e, eeee eee eeeeeeee ee eee eeeeeeee eeeeeeeee ee MM. Mee eeeeeeee eee eeeeeeee ee eeeeeeee eeeeeeee ee MeMM (8 eM) eee eeee M8M (88 eM). Mee eeeeeee eeeee eee eeeeeeeee eeee Me8M (8 × 88 eM); eee eeeeeeee eeeeeeee eeee eeeee (MeMM8) eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeeeeeeeee ee eee eeeeeee eeeee eeeeeee eeeeeeee eeee ‌888‌ ee e eeeeeeeee eeeeee; eeeee: 8.88 e (88%); ee 88–88°M/8 Meee; eeeeee 88% (MM); 8M MMM (MMMe8, δ): 8.88–8.88 (e, 8M), 8.88 (ee, 8M, M = 8.8, 8.8 Me), 8.88 (ee, 8M, M = 8.8, 8.8 Me), 8.88–8.88 (e, 8M, eeee-M).

References

Meeeeee Meeeeeeeeee

• 8.Meeeee-Meee, (8888) 88/8, 888.
• 8.Meeeee-Meee, (8888) 88/8, 888.
• 8.Meeeee-Meee, (8888) M 8e, 88.