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Please login to access the full content or check if you have access via The Classic Cope Rearrangement

DOI: 10.1055/sos-SD-203-00213

Zeh, J.; Hiersemann, M.Science of Synthesis: Stereoselective Synthesis, (20113371.

The Cope rearrangement requires relatively high temperatures to overcome the significant activation barrier; however, substituents affect the rate and transition-metal catalysts can be used to reduce the reaction temperature significantly.

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