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DOI: 10.1055/sos-SD-204-00129

MacMillan, D. W. C.; Watson, A. J. B.Science of Synthesis: Asymmetric Organocatalysis, (20121312.

Enantioselective cycloaddition reactions are a powerful method for the rapid construction of densely functionalized ring systems from relatively simple substrates. Specifically, the catalytic enantioselective DielsAlder reaction has found extensive utility within complex molecule synthesis.[‌29‌‌31‌] Consequently, this particular reaction has become a benchmark for the evaluation of new concepts within asymmetric catalysis.

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