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Please login to access the full content or check if you have access via2.3 Pauson–Khand Reactions
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Domínguez, G.; Pérez-Castells, J., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 2, 99.
General Introduction
The Pauson–Khand reaction is a rare example of a transformation that in one step produces a great increase in molecular complexity;[1–4] only a few other transformations, such as the Diels–Alder reaction or the cyclotrimerization of alkynes, can compete. The Pauson–Khand reaction occurs by the (2 + 2 + 1) cycloaddition of a triple bond, a double bond, and carbon monoxide to form a cyclopentenone (Scheme 1). Cyclopentenones are useful synthetic intermediates that can be converted into other structures, e.g. those present in natural products, or subjected to further transformation.
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References
| [1] | Mee Meeeee–Meeee Meeeeeee: Meeee, Meeeeeeeee eee Meeeeeeeeeee, Meeeee, M. M., Me.; Meeee: Meeeeee, MM, (8888). |
| [2] | Meee, M., Meeee. Meee. Mee., (8888) 888, 888. |
| [3] | Meeüeeee, M.; Meeeee, M., Mee. Meeeeeeee. Meee., (8888) 88, 888. |
| [4] | Meeeee-Meeeeee, M.; Mñeeee, M.; Méeee-Meeeeee, M.; Meeíeeeee, M.; Méeee-Meeeeeee, M., Meee. Mee. Mee., (8888) 88, 88. |
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