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DOI: 10.1055/sos-SD-120-00303

Favre-Réguillon, A.Science of Synthesis Knowledge Updatesearly view.

General Introduction

This review is an update to the previous Science of Synthesis contribution on methods for the preparation of carboxylic acids by oxidation of aldehydes and ketones (Section[‌1‌] It focuses on using green and sustainable reagents for the oxidation of aldehydes and ketones to carboxylic acids, highlighting methods using environmentally benign solvents. In oxidation reactions, fuel, oxidant, and energy are simultaneously present; therefore, process safety is important, particularly when the reaction is scaled up to the pilot plant. A very interesting discussion of this topic can be found in the publication of Cook et al.[‌2‌]