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22.1.2.3 Thioacyl Halides (Update 2024)

DOI: 10.1055/sos-SD-122-00001

Li, X.; Song, Q.Science of Synthesis Knowledge Updatesearly view.

General Introduction

Sulfur-containing functional groups feature widely in a broad spectrum of important compounds, including natural products, pharmaceuticals, and materials. As an important class of sulfur-containing compounds, thioacyl derivatives (halides and esters) have drawn much attention from organic chemists and therefore many elegant synthetic methods to access these compounds have been developed. Methods for the synthesis of thioacyl halides have been well summarized and reviewed previously in Section 22.1.2, which was published in 2005.[‌1‌] Consequently, this update is focused on the most significant advances that have been published subsequently.

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